PyNIO
PyNIO ("pie-nee-oh") is a Python module that allows read and/or write access to a variety of scientific data formats popular in climate and weather.
https://github.com/NCAR/pynio
Official documents
http://www.pyngl.ucar.edu/Nio.shtml
Imoportant announcement
NCAR has made the decision to adopt Python as the scripting language platform of choice for future development of analysis and visualization tools. As part of this decision, both NCL and PyNIO are being placed into maintenance mode. Please read this open letter to NCL users to understand what kind of impact this will have on the future of NCL and PyNIO.